Human Skin Cells Reprogrammed Into Embryonic Stem Cells
11 February 2008  UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells, without using embryos or eggs. Led by scientists Kathrin Plath and William Lowry, UCLA researchers used genetic alteration to turn back the clock on human skin cells and create cells that are nearly identical to human embryonic stem cells, which have the ability to become every cell type found in the human body. Four regulator genes were used to create the cells, which are called induced pluripotent stem cells, or iPS cells.
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Bone Marrow Stem Cell Release Regulated By Brain's Biological Clock
11 February 2008  Mount Sinai researchers have discovered that the release of blood stem cells from bone marrow is regulated by the brain through the cyclical human biological clock, via adrenergic signals transmitted by the sympathetic nervous system. These new findings point out that the harvest of stem cells for transplantation may be improved by timing it at the peak of their release.
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Stem Cells Could Eliminate Need For Anti-rejection Drugs In Transplant Patients
Chicago 24 January 2008  After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer. A team led by Joshua Miller, MD, a researcher at Northwestern University’s Feinberg School of Medicine, is working with Northwestern Memorial Hospital’s department of organ transplantation to enroll qualifying subjects in a new research study that seeks to transplants stem cells from a kidney donor’s bone marrow into the recipient, with the hope of gradually eliminating the need for anti-rejection drugs. If research proves successful, it would mean a dramatic change in the post-transplant quality of life for the transplant recipient.
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Stemagen Creates First Cloned Human Embryo
Major Advancement Towards Creating Patient-Specific and Disease-Specific Stem Cells For Therapeutic Use  January 17, 2008 – the La Jolla, California based Stemagen, a privately held embryonic stem cell research company, announced today it has become the first in the world to create, and meticulously document, a cloned human embryo using somatic cell nuclear transfer (SCNT). Stemagen CEO Samuel H. Wood, M.D., Ph.D., a co-author of the publication and a donor of the cells from which the embryos were cloned, terms this achievement “a critical milestone in the development of patient-specific embryonic stem cells for human therapeutic use, potentially including developing treatments for Parkinson’s, Alzheimer’s and other degenerative diseases.” Stemagen’s research is exhaustively detailed in a paper published in today’s issue of the highly regarded peer-reviewed scientific journal Stem Cells.
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Scientists Grow Rat Heart In Lab With Cell Implantation
14 january 2008 Scientists at the University of Minnesota with a stripped-out shell of a rat heart made it work again using new cells from a baby rat implanted inside.  All the muscle cells in a rat heart were removed leaving a scaffold of other tissues such as blood vessels and valves. Scientists then added new heart cells to the structure, which grew within two weeks to form a new beating heart with electrical impulses, and pumping a small amount of blood. It is hoped the Nature Medicine study will ultimately mean human or animal hearts can be crafted for transplant.
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